Featured Publications AM-TEAM

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Downloadable documents

  • PhD thesis Dr. Usman Rehman, co-founder of AM-TEAM; Next generation bioreactor models for wastewater treatment systems by means of detailed combined modelling of mixing and biokinetics, 2016 [DOWNLOAD]
  • BIOMATH Ghent University, Prof. Ingmar Nopens: Overview of advanced modelling R&D [DOWNLOAD]

Water and wastewater treatment

  • Nopens I, Torfs E, Ducoste J, Vanrolleghem PA, Gernaey KV. 2015. Population balance models: a useful complementary modelling framework for future WWTP modelling. Water Science & Technology. 71(2):159-167. [FULL TEXT LINK]
  • Rehman U, Veskivar M, Maere T, Guo L, Vanrolleghem PA, Nopens I. 2015. Effect of sensor location on controller performance in a wastewater treatment plant. Water Science & Technology. 71(5) [FULL TEXT LINK]
  • Gila A, Beltran G, Bejaoui MA, Sanchez S, Nopens I, Jimenez A. 2015. Modeling the settling behavior in virgin olive oil from a horizontal screw solid bowl. Journal of Food Engineering. 168(2016):148-153. [FULL TEXT LINK]
  • Hitsov I, Maere T, De Sitter K, Dotremont C, Nopens I. 2015. Modelling approaches in membrane distillation: A critical review. Separation and Purification Technology. 142(2015):48-64. [FULL TEXT LINK]
  • Laurent J, Samstag RW, Ducoste JM, Griborio A, Nopens I, Batstone DJ, Wicks JD, Saunders S, Potier O. 2014. A protocol for the use of computational fluid dynamics as a supportive tool for wastewater treatment plant modelling. Water Science & Technology. 70(10):1575-1584. [FULL TEXT LINK]
  • Van Hulle S, Vesvikar M, Poutiainen HA, Nopens I. 2014. Importance of scale and hydrodynamics for modeling anaerobic digester performance. Chemical Engineering Journal. 255:71–77. [FULL TEXT LINK]
  • Alvarado A, Veskivar M, Cisneros, Juan F, Maere T, Goethals P, Nopens I. 2013. CFD study to determine the optimal configuration of aerators in a full-scale waste stabilization pond. Water Research. 47(2013):4528-4537. [FULL TEXT LINK]
  • Ratkovich N, Horn W, Helmus FP, Rosenberger S, Naessens W, Nopens I, Bentzen TR. 2013. Activated sludge rheology: A critical review on data collection and modelling. Water Research. 47(2):463-482. [FULL TEXT LINK]
  • Audenaert W.T.M., Vandevelde M., · Van Hulle S.W.H., · Nopens I. 2013. Impact of Dissolved Organic Matter (DOM) on Parameter Sensitivity of a Kinetic Ozone Decomposition Model Ozone: Science and Engineering. 35:338–349 [FULL TEXT LINK]
  • Audenaert W.T.M., Vandierendonck, D., · Van Hulle S.W.H., · Nopens I. 2013. Comparison of ozone and HO induced conversion of effluent organic matter (EfOM) using ozonation and UV/H2O2 treatment Water Research. 47(7):2387-2398 [FULL TEXT LINK]
  • Naessens W, Maere T, Ratkovich N, Vedantam S, Nopens I. 2012. Critical review of membrane bioreactor models - Part 2: Hydrodynamic and integrated models. Bioresource Technology. 122((1)):107-118. [FULL TEXT LINK]
  • Alvarado A, Sanchez E, Durazno G, Veskivar M, Nopens I. 2012. CFD analysis of sludge accumulation and hydraulic performance of a waste stabilization pond. Water Science & Technology. 66(11):2370-2377. [FULL TEXT LINK]
  • Yang J, Vedantam S, Spanjers H, Nopens I, van Lier JB. 2012. Analysis of mass transfer characteristics in a tubular membrane using CFD modeling. Water Research. 46(15):4705-4712. [FULL TEXT LINK]
  • Alvarado A, Vedantam S, Goethals P, Nopens I. 2012. A compartmental model to describe hydraulics in a full-scale waste stabilization pond. Water Research. 46(1):[521-530] [FULL TEXT LINK]
  • Ratkovich N, Berube P, Nopens I. 2011. Assessment of mass transfer coefficients in coalescing slug flow in vertical pipes and applications to tubular airlift membrane bioreactors. Chemical Engineering Science. 66(6):1254-1268. [FULL TEXT LINK]
  • Ratkovich N, Chan C, Berube P, Nopens I. 2011. Analysis of shear stress and energy consumption in a tubular airlift membrane system. Water Science and Technology. 64(1):189-198. [FULL TEXT LINK]
  • Audenaert W.T.M., Vermeersch, Y., · Van Hulle S.W.H., · Nopens I. 2011. Application of a mechanistic UV/hydrogen peroxide model at full-scale: Sensitivity analysis, calibration and performance evaluation Chemical Engineering Journal. 171(1):113-126. [FULL TEXT LINK]
  • Audenaert W.T.M., Callewaert M., · Van Hulle S.W.H., · Nopens I. 2010. Full-scale Modelling of an Ozone Reactor for Drinking Water Treatment Chemical Engineering Journal. 157(2-3):551-557. [FULL TEXT LINK]
  • Ratkovich N, Chan CCV, Berube P, Nopens I. 2010. Investigation of the effect of viscosity on slug flow in airlift tubular membranes in search of a sludge surrogate. Water Science and Technology. 61(7):1801-1809. [FULL TEXT LINK]
  • Ratkovich N, Chan CCV, Berube P, Nopens I. 2009. Experimental study and CFD modelling of a two-phase slug flow for an airlift tubular membrane. Chemical Engineering Science. 64(16):3576-3584. [FULL TEXT LINK]
  • Nopens I,Briesen H, Ducoste J. 2009. Celebrating a milestone in Population Balance Modeling. Chemical Engineering Science. 64(4):627-627. [FULL TEXT LINK]

Bioprocess technology

  • Lencastre Fernandes R, Carlquist M, Lundin L, Heins A-L, Dutta A, Sorensen SJ, Jensen, Anker D, Nopens I, Eliasson Lantz A, Gernaey, Krist V. 2013. Cell Mass and Cell Cycle Dynamics of an Asynchronous Budding Yeast Population: Experimental Observations, Flow Cytometry Data Analysis, and Multi-Scale Modeling. Biotechnology and Bioengineering. 110(3) [FULL TEXT LINK]
  • Lencastre Fernandes R, Nierychlo M, Lundin L, Pedersen AE, Puentes Tellez PE, Dutta A, Carlquist M, Bolic A, Schäpper D, Brunetti AC et al. 2011. Experimental methods and modeling techniques for description of cell population heterogeneity. Biotechnology Advances. 29((1)):575-599. [FULL TEXT LINK]

Pharmaceutical manufacturing

  • Kumar, A.; Vercruysse, J.; Mortier, S.; Vervaet, C.; Remon, J.P.; Gernaey, K.; Nopens, I.; De Beer, T. (2016). Model-based analysis of a twin-screw granulation system for continuous solid dosage manufacturing. Computers & Chemical Engineering, 89, 62-70 [FULL TEXT LINK]
  • Kumar, A.; Dhondt, J.; Vercruysse, J.; De Leersnyder, F.; Vanhoorne, V.; Vervaet, C.; Remon, J.P.; Gernaey, K.V.; Nopens, I.; De Beer, T. (2016). Development of a process map: a step towards a regime map for steady-state high shear twin screw granulation. Powder Technology, 300, 73-82 [FULL TEXT LINK]
  • Kumar A, Alakarjula M, Vanhoorne V, Toiviainen M, De Leersnyder F, Vercruysse J, Juuti M, Ketolainen J, Vervaet C, Remon JP, Gernaey KV, Nopens I, De Beer, T. (2016). Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation. European Journal of Pharmaceutical Sciences, 90, 25-37 [FULL TEXT LINK]
  • Kumar, A.; Vercruysse, J.; Vanhoorne, V.; Toiviainen, M.; Panouillot, P.E.; Juuti, M.; Vervaet, C.; Remon, J.P.; Gernaey, K.V.; Nopens, I.; De Beer, T. (2015). Conceptual framework for model-based analysis of residence time distribution in twin-screw granulation. Eur. J. Pharm. Sci., 71, 25-34 [FULL TEXT LINK]
  • Kumar A., Vercruysse J., Bellandi G., Gernaey, K.V., Vervaet C., Remon J.P., Nopens, I.; De Beer T. (2014). Experimental investigation of granule size and shape dynamics in twin-screw granulation., Int. J. Pharmaceut, 475, 485-495 [FULL TEXT LINK]
  • Mortier, S.T.F.C., De Beer, T., Gernaey, K.V. and Nopens, I. (2014). Comparison of techniques for reconstruction of a distribution from moments in the context of a pharmaceutical drying process. Comput. Chem. Eng., 65, 1-8. [FULL TEXT LINK]
  • Kumar A., Vercruysse J., Toiviainen M., Panouillot P., Juuti M., Vanhoorne V., Gernaey K.V., Nopens I., De Beer T. (2014). Mixing and transport during pharmaceutical twin-screw wet granulation: experimental analysis via chemical imaging. European Journal of Pharmaceutics and Biopharmaceutics, 87, 279-289. [FULL TEXT LINK]
  • Mortier S.T.F.C., Gernaey K.V., Nopens I, De Beer T. (2014). Global sensitivity analysis applied to drying models for one or a population of granules. AIChE J. [FULL TEXT LINK]
  • Mortier, S.; Gernaey, K.; Nopens, I.; De Beer, T. (2014). Analysing drying unit performance in a continuous pharmaceutical manufacturing line by means of mass - energy balances. European Journal of Pharmaceutics and Biopharmaceutics, 86, 532-543. [FULL TEXT LINK]
  • Kumar A., Gernaey K.V., Nopens I., De Beer T. (2013). Modelling of High Shear Wet Granulation from Batch to Continuous Processes in Pharmaceutical Production- A Critical Review. European Journal of Pharmaceutics and Biopharmaceutics, 85(3), 814-832. [FULL TEXT LINK]
  • Mortier, S.; Van Hoey, S.; Cierkens, K.; Gernaey, K.V.; Seuntjens, P.; De Baets, B.; Nopens, I.; De Beer, T. (2013). A GLUE uncertainty analysis of a drying model of pharmaceutical granules. European Journal of Pharmaceutics and Biopharmaceutics, 85, 984-995. [FULL TEXT LINK]
  • Mortier, S.T.; De Beer, T.; Gernaey, K.; Vercruysse, J.; Fonteyne, M.; Remon, J.P.; Vervaet, C.; Nopens, I. (2012). Mechanistic modelling of the drying behaviour of single pharmaceutical granules. European Journal of Pharmaceutics and Biopharmaceutics, 80, 682-689 [FULL TEXT LINK]
  • Mortier, S.T.F.C.; Van Daele, T.; Gernaey, K.V.; Nopens, I.; De Beer, T. (2012). Reduction of a single granule drying model: an essential step in preparation of a PBM with a continuous growth term. AIChE Journal, 59, 1127-1138 [FULL TEXT LINK]
  • Mortier, S.; Gernaey, K.; Nopens, I.; De Beer, T. (2013). Development of a population balance model of a pharmaceutical drying process and testing of solution methods. Computers and Chemical Engineering, 50, 39-53. [FULL TEXT LINK]
  • Mortier, S.T.; De Beer, T.; Gernaey, K.V.; Remon, J.P.; Vervaet, C.; Nopens, I. (2011). Mechanistic modelling of fluidized bed drying processes of wet porous granules: a review. European Journal of Pharmaceutics and Biopharmaceutics, 79, 205-225. [FULL TEXT LINK]